Strain-Specific Summaries and Analyses

Choose from Complete Genomes

Choose from Incomplete/Draft Genomes

By linking from here, one can go to an overview of any reference strain's chromosome or plasmids with a summary of their genes, broken down by feature type or its product's primary subcellular localization.

Submit an Annotation Update

Submit an update to the database by email.

DNA/Amino Acid Sequences

Retrieve a specific range from genomic DNA.

Download a specific ORF's DNA or protein sequence.

Genome Projects

Burkholderia Genome Projects - A summary of complete and in-progress sequencing projects.

Burkholderia Genome Database updates and more

Welcome

The Burkholderia Genome Database facilitates the easy comparison of multiple genome annotations arising from annotation or sequence-based searches, and couples this with improved methods for ortholog identification and contextual visualization.

Funding for this work is gratefully provided by Cystic Fibrosis Foundation Therapeutics Inc., a non-profit drug discovery and development affiliate of the Cystic Fibrosis Foundation (learn more).



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Latest News

April 27, 2012

New regulatory motif data imported from the RegTransBase database (Genomics Division, Lawrence Berkeley National Laboratory ). Data consists of transcription factor binding sites and other regulatory interactions which have been manually curated and transferred to strains of the same species (when applicable) and may be viewed on intergenic region or gene details pages (example).

6 new annotation updates.

April 10, 2012

The site was down this morning between 9:30AM to 11:15AM PST due to an unexpected campus-wide power outage. As of 11:30AM, full service appears to have been restored, however please contact us if you experience any issues.

March 13, 2012

New analysis and search feature - View list of pathogen-associated genes for various Burkholderia strains. Based on the study "The association of virulence factors with genomic islands" (Ho Sui, Fedynak, Hsiao, Langille, and Brinkman (2009), PLoS ONE). Important note on this analysis: The list of genes defined as being pathogen-associated will change as more genomes are sequenced. This analysis will be updated at a later time in order to reflect this.

March 12, 2012

We've been experiencing some issues with site loading time and BLAST search errors since the last update on March 5th. We've taken steps to deal with the issue and are continuing to monitor the site to ensure it has been fixed. Sorry for any inconvenience experienced during this period. If you continue to experience problems, please contact us.

March 5, 2012

NEW FEATURE - Major upgrade to database schema to facilitate comparative genomics analysis of draft/incomplete Burkholderia genomes. Note: Incomplete/draft genomes are often poorly annotated. Therefore, it is a good idea to supplement a text search with a BLAST or ortholog search.

NEW FEATURE - View secondary genomic features including inverted repeats, terminators, transposon insertion sites on detailed gene and intergenic region pages.

NEW FEATURE - View annotations/sequences for intergenic regions in a manner similar to our detailed gene reports. View genomic features including regulatory motifs, inverted repeats, predicted transcription terminators, etc...

Added evidence for 280 translationally-verified Burkholderia pseudomallei strain 844 proteins mapped to B. pseudomallei strain K96243.

Gene cards and downloadable annotations contain information on protein physiochemical properties (molecular weight, isoelectric point, mean Kyte-Doolittle hydropathicity and net charge at pH 7).

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