Comparative Genome Search

You may use this search function to perform comparative analyses of orthologous genes (determined by reciprocal best BLAST) in order to:

1) Find orthologs present in one set of genomes (e.g. two or more strains selected from left box)

Example:
You would like to find all orthologous genes that are present in BOTH B. cenocepacia J2315 and B. cenocepacia HI2424

Steps:
a) Select B. cenocepacia J2315 and B. cenocepacia HI2424 from the left box
b) Click on submit.

2) Find orthologs present in one set of genomes (e.g. two or more strains selected from left box) while absent from another set (e.g. one or more genomes selected from right box).

Example:
You would like to find all orthologous genes that are present in BOTH B. cenocepacia J2315 and B. cenocepacia HI2424 but NOT present in B. cenocepacia AU1054.

Steps:
a) Select B. cenocepacia J2315 and B. cenocepacia HI2424 from the left box
b) Select B. cenocepacia AU1054 from the right box
c) Click on submit.

3) Find a list of genes in one strain/species that do not have orthologs in another strain/species.

Example:
You would like to find all genes in B. cenocepacia J2315 that do not have orthologs in B. cenocepacia AU1054.

Steps:
a) Select B. cenocepacia J2315 from the left box
b) Select B. cenocepacia AU1054 from the right box
c) Click on submit.

These results can be further limited by up to four boolean search fields.