• » Searching the database of genome annotations
• » Searching the log of annotation updates
• » Comparison of multiple annotations
• » Multiple alignment using ClustalW
• » BLAST search against other nucleotide and protein sequences in the database
• » How to identify orthologs in different strains/species
• » Locating orthologs from within a gene card
• » High-throughput identification and comparison of orthologs
• » How to Display and Configure Different GBrowse Tracks
• » How to view polymorphisms in closely related strains

The Burkholderia Genome database facilitates within-genome and multiple-genome comparison of annotations. In brief, the database includes the following major new features which are centered around aiding comparative analysis of Burkholderia cenocepacia strains with other species.

• Search annotations associated with any Burkholderia genome sequence who's annotations have been made available, versus just the Burkholderia cenocepacia J2315 genome. 
  
• View and compare annotations within a Burkholderia species (i.e. gene family) or between species.
• Perform multiple sequence alignments (DNA and protein) and BLAST-based searches using sequences specified during a comparison of multiple genes.
  
• Navigate between different species genomes and view alternate annotations using GBrowse.
• Customize GBrowse further to suit your needs (i.e. select and reorder annotation tracks).
• Under an individual gene view, you can view a graphic containing subcellular localization information for the protein associated with that gene, and there is an expanded list of links to other resources (more functional category information, links to other genome databases when suitable, etc.).
  
• Perform DNA Motif searches.
• View polymorphisms/SNPs in closely-related Burkholderia genomes.