Strain |
Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest |
Locus Tag |
BPSL3110
|
Name |
tssK-1
|
Replicon | chromosome 1 |
Genomic location | 3715048 - 3716394 (+ strand) |
Comment | Gene is part of a cluster known as the type VI secretion system gene cluster tss-1 used in much of the early P. pseudomallei literature (PMID:17660433) but later referred to as T6SS-1 cluster later (PMID:22007185) |
RefSeq | YP_109705.1 |
GI | 53720719 |
Entrez | 3094306 |
GI | 53720719 |
INSDC | CAH37121.1 |
NCBI Locus Tag | BPSL3110 |
RefSeq | YP_109705.1,GeneID |
UniParc | UPI000043B620 |
UniProtKB Acc | Q63QB3 |
UniProtKB ID | Q63QB3_BURPS |
UniRef100 | UniRef100_A0A069B5D1 |
UniRef50 | UniRef50_A0A031GUJ4 |
UniRef90 | UniRef90_A0A0B6RHV8 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
type VI secretion system protein TssK-1
|
Synonyms |
hypothetical protein |
Evidence for Translation |
Detected in B. pseudomallei strain DD503 using trypsin shaving and mass spectrometry (PMID:21391724).
|
Charge (pH 7) | -9.68 |
Kyte-Doolittle Hydrophobicity Value | -0.038 |
Molecular Weight (kDa) | 49758.1 |
Isoelectric Point (pI) | 5.73 |
Individual Mappings | |
Additional evidence for subcellular localization |
Detected in Triton-insoluble fraction of lysozyme-treated B. pseudomallei DD503 cells using trypsin shaving and mass spectrometry (PMID:21391724).
|
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 108 genera
|
Burkholderia Ortholog Group |
BG000363 (632 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BPSL3110
Search term: tssK-1
Search term: type VI secretion system protein TssK-1
|
Quantitative proteomic analysis of Burkholderia pseudomallei Bsa type III secretion system effectors using hypersecreting mutants.
Vander Broek CW, Chalmers KJ, Stevens MP, Stevens JM
Mol Cell Proteomics 2015 Apr;14(4):905-16
PubMed ID: 25635268
|
In vivo expression technology identifies a type VI secretion system locus in Burkholderia pseudomallei that is induced upon invasion of macrophages.
Shalom G, Shaw JG, Thomas MS
Microbiology 2007 Aug;153(Pt 8):2689-2699
PubMed ID: 17660433
|
Strategies for Intracellular Survival of Burkholderia pseudomallei.
Allwood EM, Devenish RJ, Prescott M, Adler B, Boyce JD
Front Microbiol 2011;2:170
PubMed ID: 22007185
|
Type VI secretion is a major virulence determinant in Burkholderia mallei.
Schell MA, Ulrich RL, Ribot WJ, Brueggemann EE, Hines HB, Chen D, Lipscomb L, Kim HS, Mrázek J, Nierman WC, Deshazer D
Mol Microbiol 2007 Jun;64(6):1466-85
PubMed ID: 17555434
|