Strain |
Burkholderia pseudomallei K96243 - Assembly GCF_000011545.1
GCF_000011545.1|latest |
Locus Tag |
BPSS1621
|
Name |
bpscU2
Synonym: sctU |
Replicon | chromosome 2 |
Genomic location | 2196386 - 2197468 (- strand) |
Comment | This gene is part of the type III secretion system T3SS-2 locus found in B. pseudomallei. B. pseudomallei T3SS-1 and T3SS-2, but not T3SS-3 contribute to pathogenicity in Solanum lycopersicum (tomato) but not human monocytic cell line THP-1. (PMID:20109238). |
RefSeq | YP_111629.1 |
GI | 53722644 |
Entrez | 3096071 |
GI | 53722644 |
INSDC | CAH39096.1 |
NCBI Locus Tag | BPSS1621 |
RefSeq | YP_111629.1,GeneID |
UniParc | UPI000043BD78 |
UniProtKB Acc | Q63JU3 |
UniProtKB ID | Q63JU3_BURPS |
UniRef100 | UniRef100_Q63JU3 |
UniRef50 | UniRef50_Q3JKR4 |
UniRef90 | UniRef90_Q3JKR4 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
autoprotease, early/middle substrate switch BpscU2 (T3SS-2)
|
Synonyms |
type III secretion system protein HrcU |
Evidence for Translation | |
Charge (pH 7) | 12.63 |
Kyte-Doolittle Hydrophobicity Value | 0.192 |
Molecular Weight (kDa) | 38914.3 |
Isoelectric Point (pI) | 10.28 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 324 genera
|
Burkholderia Ortholog Group |
BG017459 (457 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BPSS1621
Search term: bpscU2
|
Type III secretion system cluster 3 is required for maximal virulence of Burkholderia pseudomallei in a hamster infection model.
Warawa J, Woods DE
FEMS Microbiol Lett 2005 Jan 1;242(1):101-8
PubMed ID: 15621426
|
Type III Secretion in the Melioidosis Pathogen <i>Burkholderia pseudomallei</i>.
Vander Broek CW, Stevens JM
Front Cell Infect Microbiol 2017;7:255
PubMed ID: 28664152
|