Strain |
Burkholderia thailandensis E264 ATCC 700388
GCF_000012365.1|latest |
Locus Tag |
BTH_II2087
|
Name |
malR
Synonym: btaR4 |
Replicon | chromosome II |
Genomic location | 2543245 - 2544522 (- strand) |
Transposon Mutants | 2 transposon mutants in E264 ATCC 700388 |
Comment | Belongs to the malleilactone biosynthetic gene cluster |
RefSeq | YP_440275.1 |
GI | 83716463 |
Entrez | 3845671 |
GI | 83716463 |
INSDC | ABC34352.1 |
NCBI Locus Tag | BTH_II2087 |
RefSeq | YP_440275.1 |
UniParc | UPI00006673FF |
UniProtKB Acc | Q2T3H4 |
UniProtKB ID | Q2T3H4_BURTA |
UniRef100 | UniRef100_Q2T3H4 |
UniRef50 | UniRef50_Q3JHD3 |
UniRef90 | UniRef90_Q2T3H4 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
MalR
|
Synonyms |
ATP-dependent transcription regulator LuxR |
Evidence for Translation | |
Charge (pH 7) | 44.21 |
Kyte-Doolittle Hydrophobicity Value | -0.308 |
Molecular Weight (kDa) | 47074.4 |
Isoelectric Point (pI) | 11.84 |
Individual Mappings | |
Additional evidence for subcellular localization |
Source 1 | |
Database | VFDB : VF0433 |
Category | Quorum sensing system |
Evidence |
ECO:0000250
sequence similarity evidence used in manual assertion
|
Host Organism | |
Notes | |
Annotation transferred from | Burkholderia pseudomallei K96243 |
Reference | 17984080 |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 221 genera
|
Burkholderia Ortholog Group |
BG019771 (338 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BTH_II2087
Search term: malR
Search term: MalR
|
Global Awakening of Cryptic Biosynthetic Gene Clusters in Burkholderia thailandensis.
Gupta A, Bedre R, Thapa SS, Sabrin A, Wang G, Dassanayake M, Grove A
ACS Chem Biol 2017 Dec 15;12(12):3012-3021
PubMed ID: 29087175
|
Malleilactone, a polyketide synthase-derived virulence factor encoded by the cryptic secondary metabolome of Burkholderia pseudomallei group pathogens.
Biggins JB, Ternei MA, Brady SF
J Am Chem Soc 2012 Aug 15;134(32):13192-5
PubMed ID: 22765305
|