Burkholderia multivorans DDS 15A-1, DM80_RS04270 (ampC1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Feature Overview

Strain Burkholderia multivorans DDS 15A-1
GCF_000756005.1|latest
Locus Tag
DM80_RS04270
NCBI Old Locus TagDM80_6457
Name
ampC1
Synonym: ampC
Replicon chromosome 3
Genomic location 963674 - 964843 (- strand)

Cross-References

RefSeq WP_012218336.1
GI 501174646
NCBI Locus Tag DM80_RS04270
NCBI Old Locus Tag DM80_6457
RefSeq WP_012218336.1,GeneID

Product

Feature Type CDS
Coding Frame 1
Product Name
class C beta-lactamase
Product Name Confidence: Class 2
Synonyms AmpC1
Evidence for Translation
Charge (pH 7) 9.19
Kyte-Doolittle Hydrophobicity Value 0.015
Molecular Weight (kDa) 41875.9
Isoelectric Point (pI) 9.89

Subcellular localization

Individual Mappings
Localization Confidence PMID
Periplasmic Class 3
Extracellular Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Pathogen Association Analysis

Results Analysis not done

Orthologs/Comparative Genomics

Burkholderia Ortholog Group BG005235 (327 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: DM80_RS04270
Search term: ampC1

Human Homologs

References

Characterization of the AmpC beta-Lactamase from Burkholderia multivorans.
Becka SA, Zeiser ET, Barnes MD, Taracila MA, Nguyen K, Singh I, Sutton GG, LiPuma JJ, Fouts DE, Papp-Wallace KM
Antimicrob Agents Chemother 2018 Oct;62(10)
PubMed ID: 30012762