Strain |
Burkholderia cenocepacia J2315
GCF_000009485.1|latest |
Locus Tag |
BCAL1929
|
NCBI Locus Tag | QU43_RS46190 |
Name |
arnT
|
Replicon | chromosome 1 |
Genomic location | 2128443 - 2130119 (+ strand) |
Comment | In PMID:27597847: arnT, arnB, arnC, arnA1, arnA2, and BCAL1935 located in the arn gene cluster harbored significantly low frequencies of transposon insertions (TraDIS). They were therefore categorized as essential by the authors. |
RefSeq | WP_006482861.1 |
GI | 206560293 |
Entrez | 6932119 |
GI | 206560293 |
INSDC | CAR52230.1 |
NCBI Locus Tag | QU43_RS46190 |
NCBI Old Locus Tag | BCAL1929 |
RefSeq | WP_006482861.1,GeneID |
UniParc | UPI00017B921E |
UniProtKB Acc | B4EB15 |
UniProtKB ID | B4EB15_BURCJ |
UniRef100 | UniRef100_A0A0D1BVQ3 |
UniRef50 | UniRef50_E5AQP3 |
UniRef90 | UniRef90_A9AG56 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
4-amino-4-deoxy-L-arabinose transferase ArnT
|
Synonyms |
aminoarabinose transferase putative undecaprenyl phosphate-alpha-4-amino-4-deoxy-l-arabinose arabinosy transferase |
Evidence for Translation | |
Charge (pH 7) | 18.09 |
Kyte-Doolittle Hydrophobicity Value | 0.493 |
Molecular Weight (kDa) | 62686.3 |
Isoelectric Point (pI) | 10.12 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 249 genera
|
Burkholderia Ortholog Group |
BG001691 (653 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: BCAL1929
Search term: arnT
Search term: 4-amino-4-deoxy-L-arabinose transferase ArnT
|
A putative gene cluster for aminoarabinose biosynthesis is essential for Burkholderia cenocepacia viability.
Ortega XP, Cardona ST, Brown AR, Loutet SA, Flannagan RS, Campopiano DJ, Govan JR, Valvano MA
J Bacteriol 2007 May;189(9):3639-44
PubMed ID: 17337576
|
PubMed ID: 22742453
|
ArnT proteins that catalyze the glycosylation of lipopolysaccharide share common features with bacterial N-oligosaccharyltransferases.
Tavares-Carreón F, Fathy Mohamed Y, Andrade A, Valvano MA
Glycobiology 2016 Mar;26(3):286-300
PubMed ID: 26515403
|
Burkholderia cenocepacia and Salmonella enterica ArnT proteins that transfer 4-amino-4-deoxy-l-arabinose to lipopolysaccharide share membrane topology and functional amino acids.
Tavares-Carreón F, Patel KB, Valvano MA
Sci Rep 2015 Jun 1;5:10773
PubMed ID: 26030265
|
An inner membrane enzyme in Salmonella and Escherichia coli that transfers 4-amino-4-deoxy-L-arabinose to lipid A: induction on polymyxin-resistant mutants and role of a novel lipid-linked donor.
Trent MS, Ribeiro AA, Lin S, Cotter RJ, Raetz CR
J Biol Chem 2001 Nov 16;276(46):43122-31
PubMed ID: 11535604
|
Candidate Essential Genes in Burkholderia cenocepacia J2315 Identified by Genome-Wide TraDIS.
Wong YC, Abd El Ghany M, Naeem R, Lee KW, Tan YC, Pain A, Nathan S
Front Microbiol 2016;7:1288
PubMed ID: 27597847
|